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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF2
All Species:
16.67
Human Site:
S718
Identified Species:
40.74
UniProt:
O14827
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14827
NP_008840.1
1237
140764
S718
E
H
L
V
D
G
K
S
P
R
L
C
R
K
F
Chimpanzee
Pan troglodytes
XP_517672
1237
140775
S718
E
H
L
V
D
G
K
S
P
R
L
C
R
K
F
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
K42
D
N
T
K
W
Q
T
K
W
F
A
L
L
Q
N
Dog
Lupus familis
XP_852734
1350
152162
S718
E
H
L
V
D
G
K
S
P
R
L
C
R
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P70392
1189
135649
A703
R
S
L
E
L
F
F
A
T
S
Q
N
N
R
E
Rat
Rattus norvegicus
Q99JE4
1190
135808
A703
R
S
L
E
L
F
F
A
T
S
Q
N
N
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
S722
E
Y
L
V
D
G
K
S
P
H
V
C
R
K
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
S714
G
D
H
V
N
D
K
S
P
R
L
C
R
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
P218
D
A
V
L
V
E
D
P
N
D
L
G
T
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
N713
D
P
H
H
S
H
G
N
Q
Y
E
N
S
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
31.3
87.1
N.A.
91.1
91.2
N.A.
91.2
N.A.
N.A.
85.4
N.A.
N.A.
25.4
N.A.
48.5
Protein Similarity:
100
99.7
36.2
89.2
N.A.
93.5
93.6
N.A.
95.1
N.A.
N.A.
91.6
N.A.
N.A.
37
N.A.
64.7
P-Site Identity:
100
100
0
100
N.A.
6.6
6.6
N.A.
80
N.A.
N.A.
66.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
20
20
N.A.
93.3
N.A.
N.A.
73.3
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
20
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% C
% Asp:
30
10
0
0
40
10
10
0
0
10
0
0
0
0
10
% D
% Glu:
40
0
0
20
0
10
0
0
0
0
10
0
0
0
20
% E
% Phe:
0
0
0
0
0
20
20
0
0
10
0
0
0
0
50
% F
% Gly:
10
0
0
0
0
40
10
0
0
0
0
10
0
0
0
% G
% His:
0
30
20
10
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
50
10
0
0
0
0
0
50
0
% K
% Leu:
0
0
60
10
20
0
0
0
0
0
50
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
10
10
0
0
30
20
0
10
% N
% Pro:
0
10
0
0
0
0
0
10
50
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
20
0
0
10
0
% Q
% Arg:
20
0
0
0
0
0
0
0
0
40
0
0
50
20
0
% R
% Ser:
0
20
0
0
10
0
0
50
0
20
0
0
10
0
0
% S
% Thr:
0
0
10
0
0
0
10
0
20
0
0
0
10
0
0
% T
% Val:
0
0
10
50
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _